解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Cell Suspension cultures of THAMNOSMA MONTANA were grown in Gamborg B5 medium which was best suited for acridone alkaloid formation. From the lyophilized cell material nine acridones and three acridone-monoglucosides have been isolated which were found for the first time in the genus THAMNOSMA. Moreover, N-methylacrid...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959437
更新日期:1994-04-01 00:00:00
abstract::Stem extracts of Styrax camporum Pohl and Caesalpinia ferrea Martius were administered orally and intraperitoneally to rats and effected a decrease in the acute ulceration number. The volume, pH, and hydrochloric acid concentration of gastric secretions were measured after administration of both extracts, atropine, an...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959430
更新日期:1994-04-01 00:00:00
abstract::A radioimmunoassay as well as an enzyme immunoassay for the quantitation of fmol amounts of the alkaloid colchicine have been developed. The antiserum used for both assays was raised against a conjugate of colchicoside-bovine serum albumin. The crude serum was satisfactory for the performance of the radioimmunoassay. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959413
更新日期:1994-02-01 00:00:00
abstract::There is an obvious discrepancy between the popularity of mistletoe extracts and their classification as a non-conventional treatment modality with unproven efficacy in oncology. The commercial preparations suffer from several major drawbacks: lack of precise declarations for the molecular characteristics and the conc...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-2006-959396
更新日期:1994-02-01 00:00:00
abstract::A new compound kaempferol 3-O-alpha-L-(2"-E-p-coumaroyl)-rhamnopyranoside, as well as the known flavonoids, kaempferol 3-O-beta-D-(6"-E-p-coumaroyl)-glucopyranoside, kaempferol 3-O-alpha-L-(2",3"-di-E-p-coumaroyl)-rhamnopyranoside, and caffeic acid were obtained from the methanolic extract of Platanus orientalis L. bu...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959751
更新日期:1993-12-01 00:00:00
abstract::Four antiplatelet components were isolated from Arnebia euchroma. They inhibited the aggregation of washed rabbit platelets caused by collagen, arachidonic acid, platelet-activating factor, ADP, or thrombin. The potency of inhibiting collagen-induced platelet aggregation is in the following order: acetylshikonin (IC50...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959718
更新日期:1993-10-01 00:00:00
abstract::The structure of isoselagine, isolated from the Chinese medicinal plant LYCOPODIUM SERRATUM Thunb. var. longipetiolatum Spring, was shown to be identical with huperzine A ( 1) and to have an exocyclic double bond in the E -configuration from NOE data. In the process of extraction of isoselagine, we also isolated and i...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959735
更新日期:1993-10-01 00:00:00
abstract::The hypoglycaemic effect of orally administered extracts of leaves and roots of Coccinia indica has been reported earlier. The oral administration of the pectin isolated from the fruit of the above plant at a dose of 200 mg/100 g BW/day showed a significant hypoglycaemic action in normal rats. Pectins isolated from ma...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959693
更新日期:1993-08-01 00:00:00
abstract::Seven phenolic derivatives, 2,4-bis(4-hydroxybenzyl)phenol ( 1), bis[4(beta- D-glucopyranosyloxy)-benzyl] ( S)-(-)-2-isopropylmalate ( 2), bis[4-(beta- D-gluco-pyranosyloxy)benzyl] ( S)-(-)-2-sec-butylmalate ( 3), 4-hydroxybenzyaldehyde ( 4), 4,4'-dihydroxydiphenyl-methane ( 5), 4-hydroxybenzyl alcohol ( 6), and 4-(be...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959702
更新日期:1993-08-01 00:00:00
abstract::We report the effects of a fraction (F1) obtained from Himanthalia elongata on spontaneous locomotor activity, hypermotility, motor coordination, rectal temperature, pentobarbitone-induced hypnosis, pentylenetetrazole-induced convulsions and analgesic activity in the writhing and hot-plate tests. This fraction caused ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959655
更新日期:1993-06-01 00:00:00
abstract::A beta-hydroxychalcone 1, so far not reported as a natural compound, was separated from the diethyl ether extract of LEPTOSPERMUM SCOPARIUM (Myrtaceae). Furthermore, three known flavonoids 2-4 were isolated. The (13)C-NMR spectra of 2-4 are reported, since they have as yet not been reported in the literature. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959667
更新日期:1993-06-01 00:00:00
abstract::Geraniol dehydrogenase, the specific enzyme involved in geraniol to citral TRANS (geranial) transformation, activity was monitored in various lemongrass cultivars differing in amounts and relative percentages of citral and geraniol in their essential oils. The enzyme activity had a positive and significant association...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959636
更新日期:1993-04-01 00:00:00
abstract::In this work we studied the effect of alpha-asarone, a hypolipidemic active principle of Guatteria gaumeri Greenman, on hepatic lipid metabolism using adult rat hepatocytes cultured on a feeder layer of 3T3 cells. These cultures synthesize and secrete for at least two weeks various lipids from [14C]-acetic and [14C]-o...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959625
更新日期:1993-04-01 00:00:00
abstract::A new minor diterpenoid alkaloid, caeruline, was isolated from DELPHINIUM CAERULEUM Jacq. ex Camb. Its structure was elucidated as 1 on the basis of spectral evidence. Along with this new compound, three known diterpenoid alkaloids were also isolated from this plant and identified as tatsiensine, delcosine, and lycoct...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959611
更新日期:1993-02-01 00:00:00
abstract::Picroliv, a standardized extract from the plant Picrorhiza kurrooa containing active constituents, showed a significant dose dependent (3-12 mg/kg p.o. x 7) protective activity against galactosamine-induced hepatic damage in rat as evaluated on the isolated hepatocytes (ex vivo) preparation. It markedly increased the ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959600
更新日期:1993-02-01 00:00:00
abstract::Three new secoiridoid glucosides, jasamplexosides A, B and C, were isolated from the crude drug "Niu du teng", the leaves and stems of JASMINUM AMPLEXICAULE, together with the known secoiridoid glucosides, 10-hydroxyligstroside and jasminoside. Their structural elucidation by spectroscopic studies is described. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-961548
更新日期:1992-12-01 00:00:00
abstract::The hypoglycemic activity of olive leaf was studied. Maximum hypoglycemic activity was obtained from samples collected in the winter months, especially in February. One of the compounds responsible for this activity was oleuropeoside, which showed activity at a dose of 16 mg/kg. This compound also demonstrated antidia...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-961538
更新日期:1992-12-01 00:00:00
abstract::The aerial parts of CUNILA SPICATA Benth., a Brasilian Lamiaceae, afforded a sesquiterpene-aldehyde named isocaryophyllen-13-al (beta-betulenal) ( 1). The constitution and configuration of this compound were established by high field NMR-techniques for the first time. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-961509
更新日期:1992-10-01 00:00:00
abstract::The preventive effects of hydroxychalcone derivatives on ulcer formation induced by severe necrotizing agents such as 60% ethanol in 150 mM HCl (HCl-ethanol) and 0.2 N NaOH in rats were examined. Among the compounds tested, 2',4'-dihydroxychalcone gave the strongest activity in both experimental models and protected t...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-961498
更新日期:1992-10-01 00:00:00
abstract::The inhibitory action of the major constituent of Genista tridentata L. (Papilionaceae), 4',5,7-trihydroxyisoflavone (genistein), on contractions induced by agonists and electrical field stimulation of smooth muscle was analysed. Genistein inhibited twitches evoked by electrical-stimulation of strips of guinea-pig ile...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-961474
更新日期:1992-08-01 00:00:00
abstract::Capillary GC, GC-MS, IR, GC-IR, (1)H- and (13)C-NMR studies of the essential oil from the leaves and cones of ELSHOLTZIA POLYSTACHYA collected from two different locations in India revealed that one oil contained 1,8-cineol (37.3%), the other one perillene (61.2%) as the main constituent. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-961490
更新日期:1992-08-01 00:00:00
abstract::Immune complex binding to macrophages was enhanced by treatment with an E. kansui extract. Systematic fractionation of the extract led to the characterization of 3-O-(2'E,4'Z-decadienoyl)- and 3-O-(2,3-dimethylbutyryl)-13- O-n-dodecanoyl-13-hydroxyingenol as the active principles. Immune complex binding to macrophages...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-961447
更新日期:1992-06-01 00:00:00
abstract::From the bark of Sclerocarya birrea was isolated (-)-epicatechin-3-galloyl ester of which the structure was elucidated by NMR spectroscopy. The compound has secretagogue activity. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-961423
更新日期:1992-04-01 00:00:00
abstract::The chemical composition of the essential oil of CYMBOPOGON TRAVANCORENSIS Bor. (Poaceae) was investigated by capillary GC and GC-MS. Thirty-five compounds were identified. The oil contains mono- and sesquiterpene hydrocarbons (39.60%), oxygenated terpenes (30.45%), and phenyl propanoids (22.04%). The main constituent...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-961434
更新日期:1992-04-01 00:00:00
abstract::Two triterpenoidal saponins having phytolaccagenin as the aglycone were isolated from the roots of Phytolacca esculenta (Phytolaccaceae). The structures of two new saponins, esculentoside I and esculentoside N, were established to be 3-O-[beta-D-glucopyranosyl-(1----4)-beta-D- glucopyranosyl]-28-O-beta-D-glucopyranosy...
journal_title:Planta medica
pub_type: 杂志文章
doi:
更新日期:1992-02-01 00:00:00
abstract::N-Deacetylcolchiceine (DAC) administered i.p. to rats decreased the level of serum cholesterol and apoB. It was accompanied by the fall of HDL-C due to the decrease of both HDL subfractions HDLa and HDLb, and by a rather weaker decrease of LDL-C. The levels of serum and lipoprotein triacylglycerols were not significan...
journal_title:Planta medica
pub_type: 杂志文章
doi:
更新日期:1992-02-01 00:00:00
abstract::The nature of gene action for biomass yield and tropane alkaloid content was ascertained through diallel analysis in Egyptian henbane, HYOSCYAMUS MUTICUS L. Dominance variation was preponderant over additive genetic variance, dominance being in the overdominance range for both traits. On an overall basis, recessive al...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-961395
更新日期:1992-02-01 00:00:00
abstract::The crude extract (IPA) of the plant Ipomoea pes-caprae (L.) R. Br. showed an inhibitory effect on prostaglandin synthesis in vitro. Bioassay-guided separation of the extract led to the isolation of four active compounds: 2-hydroxy-4,4,7-trimethyl-1(4H)-naphthalenone (1), (-)-mellein (2), eugenol (3), and 4-vinyl-guai...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960196
更新日期:1991-12-01 00:00:00
abstract::Ginsenoside Ro, an oleanane-type saponin has been screened for activity in experimental models of acute and chronic hepatitis. Ginsenoside Ro (50 and 200 mg/kg, P.O.) inhibited the increase of serum glutamic oxaloacetic transaminase (s-GOT) and serum glutamic pyruvic transaminase (s-GPT) levels in D-galactosamine (Gal...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960198
更新日期:1991-12-01 00:00:00
abstract::Increasingly, as a result of recent biochemical work, there exists a realistic possibility of taking a molecular genetic approach to the manipulation of alkaloid-producing pathways in plant tissue cultures. In the pathways forming indole alkaloids in CATHARANTHUS ROSEUS, tropane alkaloids in DATURA and HYOSCYAMUS spec...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960226
更新日期:1991-10-01 00:00:00
abstract::Tissue callus cultures originating from CHELIDONIUM MAJUS L. seeds were established on Gamborg B5, Murashige-Skoog (MS), and Schenk-Hildebrandt (SH) media. In all experimental conditions, calli accumulated a complex pattern of isoquinoline derivatives. The highest values, both in growth and in sanguinarine production,...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960141
更新日期:1991-10-01 00:00:00
abstract::Natural compounds have been the first historical source of antithrombotic compounds (heparin, vitamin K antagonists, streptokinase, urokinase); molecules extracted from plants or animals still provide some of the most original and promising approaches for the discovery of new drugs in this class. In this review, we wi...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:
更新日期:1991-10-01 00:00:00
abstract::Two new 8-oxotetrahydroprotoberberine alkaloids, gusanlung A(1) and B(2), together with known isoquinoline alkaloids, berberine and jatrorrhizine, were isolated from the Chinese medicinal plant Acangelisia gusanlung H. S. Lo (Menispermaceae). Their structures were elucidated mainly by spectroscopic analysis. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960150
更新日期:1991-10-01 00:00:00
abstract::d-Dicentrine was isolated from the root of Lindera megaphylla. It inhibited the aggregation of washed rabbit platelets induced by ADP, collagen, arachidonic acid, and PAF. It also inhibited the high potassium- and norepinephrine-induced contraction of rat thoracic aorta. In rat ventricular cells treated with 3 microM ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960135
更新日期:1991-10-01 00:00:00
abstract::The indole alkaloid content of RAUWOLFIA SERPENTINA roots from regenerated plants (from stem-and root-callus) was compared with the parental stock. Although the total alkaloid content seems to be slightly higher in the roots from regenerated plants, HPLC-analysis of individual alkaloids indicated that the contents of ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960109
更新日期:1991-08-01 00:00:00
abstract::In garlic (Allium sativum L.) the enzyme alliin lyase catalyzes the cleavage of alliin into allicin which reacts further to furnish ajoene. A simultaneous determination of allicin and ajoene is introduced which, in contrast to the determination of alliin only, allows for the testing of the activity of alliin lyase. It...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960120
更新日期:1991-08-01 00:00:00
abstract::Plumbagin, an active principle from Plumbaginaceous plants, produced a triphasic inotropic response (first positive, second negative, and third positive phases) in guinea-pig papillary muscle. The inotropic potency of plumbagin at the first positive phase was pD2 6.40, and the methylation of 5-hydroxy group of plumbag...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960106
更新日期:1991-08-01 00:00:00
abstract::Lyophilised aqueous extract of Euphorbia hirta L. (Euphorbiaceae) has been evaluated for analgesic, antipyretic and anti-inflammatory properties in mice and rats, in order to complete its activity profile, after the confirmation of the existence of a central depressant activity particularly expressed by a strong sedat...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960079
更新日期:1991-06-01 00:00:00
abstract::From the leaves of BLUMEA ARFAKIANA Martelli (Asteraceae), used in traditional medicine in Papua New Guinea, besides stigmasterol and beta-eudesmol, four graniline esters ( 1-4) have been isolated. Furthermore, blumealactone C ( 5), deacetylblumealactone C ( 6), and deoxyblumealactone C ( 7) have been identified. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960090
更新日期:1991-06-01 00:00:00
abstract::Eschsholzia californica Cham. is a traditional medicinal plant of the Indians used by the rural population of California for its analgesic and sedative properties. Our study on the aqueous extract shows that this plant reduced the behavioural parameters measured in a familiar environment test in mice (novelty preferen...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960076
更新日期:1991-06-01 00:00:00